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Article

Characterization of two hydrophobic methyl clusters in HIV-1 protease by NMR spin relaxation in solution.

Journal of molecular biology - 19 Jan 2001

Ishima R, Louis J M, Torchia D A

Abstract excerpt

Nearly 50 % of the amino acid residues of HIV-1 protease contain methyl side-chains, most of which appear to be organized into two clusters: the inner cluster that nearly surrounds the active site and the outer cluster that contains the hydrophobic core which stabilizes the inhibitor-free proteas...

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Identifiers

PMID: 11152609
DOI: 10.1006/jmbi.2000.4321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11152609-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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