Article
Major histocompatibility complex class I associations in iron overload: evidence for a new link between the HFE H63D mutation, HLA-A29, and non-classical forms of hemochromatosis.
Immunogenetics - 1 Apr 1998
Porto G, Alves H, Rodrigues P, Cabeda J M, Portal C, Ruivo A, Justiça B, Wolff R, De Sousa M
Abstract excerpt
The present study is an analysis of the frequencies of HFE mutations in patients with different forms of iron overload compared with the frequencies found in healthy subjects from the same region. The frequencies of HLA-A and -B antigens and HLA haplotypes were also analyzed in the same subjects....
Topics
- Adult
- Aged
- Aged, 80 and over
- Female
- Ferritins
- Gene Frequency
- Genetic Linkage
- HLA Antigens
- HLA-A Antigens
- HLA-B Antigens
- Haplotypes
- Hemochromatosis
- Hemochromatosis Protein
- Histocompatibility Antigens Class I
- Humans