Article
Retinoic acid inhibits downregulation of DeltaNp63alpha expression during terminal differentiation of human primary keratinocytes.
The Journal of investigative dermatology - 1 Jan 2002
Bamberger Casimir, Pollet Dieter, Schmale Hartwig
Abstract excerpt
Recently, the p53 homolog p63 has been implicated in sustaining the epidermal stem cell population. The p63 gene encodes six major products with transactivating or dominant-negative properties. The expression pattern of these isoforms in keratinocytes was investigated here. Northern blot, ribonuclease protection assay, reverse transcription-polymerase chain reaction, and western blot techniques sensitive for all...
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