Article
A dominant negative form of p63 inhibits apoptosis in a p53-independent manner.
Biochemical and biophysical research communications - 26 May 2006
Lee Hae-ock, Lee Jung-Hwa, Choi Eunhee, Seol Ja Young, Yun Yungdae, Lee Hyunsook
Abstract excerpt
Stem cells are a source of differentiated cells in multiple tissues. If genetic alterations occur in stem cells, the problem persists and malignant cancers may arise. DeltaNp63alpha-a homologue of the tumor suppressor p53-is exclusively expressed in proliferating undifferentiated epithelial cells...
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