Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p63 identifies keratinocyte stem cells

13 Mar 2001

Abstract excerpt

The proliferative compartment of stratified squamous epithelia consists of stem and transient amplifying (TA) keratinocytes. Some polypeptides are more abundant in putative epidermal stem cells than in TA cells, but no polypeptide confined to the stem cells has yet been identified. Here we show that the p63 transcription factor, a p53 homologue essential for regenerative proliferation in epithelial development,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Corneal Surgery and Treatments
Share to Developmental Biology and Gene Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11248048
DOI: 10.1073/pnas.061032098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p63 identifies keratinocyte stem cellsPMID 11248048Read ↗

Location and Clonal Analysis of Stem Cells and Their Differentiated Progeny in the Human Ocular SurfaceSemantic proximity Read ↗

Isoforms of ΔNp63 and the migration of ocular limbal cells in human corneal regenerationSemantic proximity Read ↗

The ΔNp63α Phosphoprotein Binds the p21 and 14-3-3σ Promoters In Vivo and Has Transcriptional Repressor Activity That Is Reduced by Hay-Wells Syndrome-Derived MutationsSemantic proximity Read ↗

p63: Defining roles in morphogenesis, homeostasis, and neoplasia of the epidermisSemantic proximity Read ↗

Master regulatory role of p63 in epidermal development and disease.Semantic proximity Read ↗

Interleukin 6 and STAT 3 regulate p63 isoform expression in keratinocytes during regenerationSemantic proximity Read ↗

P63 expression levels in side population and low light scattering ocular surface epithelial cells.Semantic proximity Read ↗

Induced multipotency in adult keratinocytes through down-regulation of <i>ΔNp63</i> or <i>DGCR8</i>Semantic proximity Read ↗

Retinoic acid inhibits downregulation of DeltaNp63alpha expression during terminal differentiation of human primary keratinocytes.Semantic proximity Read ↗

p63 maintains keratinocyte proliferative capacity through regulation of Skp2–p130 levelsSemantic proximity Read ↗

Stem cells of the adult cornea: From cytometric markers to therapeutic applicationsSemantic proximity Read ↗

Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.