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Article

Comparison of the folding processes of T. thermophilus and E. coli ribonucleases H.

Journal of molecular biology - 15 Feb 2002

Hollien Julie, Marqusee Susan

Abstract excerpt

In order to examine how the stabilization of thermophilic proteins affects their folding, we have characterized the folding process of Thermus thermophilus ribonuclease H using circular dichroism, fluorescence, and pulse-labeling hydrogen exchange. Like its homolog from Escherichia coli, this thermophilic protein populates a partially folded kinetic intermediate within the first few milliseconds of folding. The...

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Identifiers

PMID: 11851342
DOI: 10.1006/jmbi.2001.5346

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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