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Article

Salt bridge as a gatekeeper against partial unfolding.

Protein science : a publication of the Protein Society - 1 May 2016

Hinzman Mark W, Essex Morgan E, Park Chiwook

Abstract excerpt

Salt bridges are frequently observed in protein structures. Because the energetic contribution of salt bridges is strongly dependent on the environmental context, salt bridges are believed to contribute to the structural specificity rather than the stability. To test the role of salt bridges in enhancing structural specificity, we investigated the contribution of a salt bridge to the energetics of native-state...

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Identifiers

PMID: 26916981
DOI: 10.1002/pro.2908
PMCID: PMC4838642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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