Ethidium bromide exposure unmasks an antibiotic efflux system in Rhodococcus equi

doi:10.1093/jac/dkab121

Article

Ethidium bromide exposure unmasks an antibiotic efflux system in Rhodococcus equi

24 Mar 2021

Abstract excerpt

BACKGROUND: This study introduces a newly created strain (Rhodococcus equiEtBr25) by exposing R. equi ATCC 33701 to ethidium bromide (EtBr), a substrate for MDR transporters. Such an approach allowed us to investigate the resulting phenotype and genetic mechanisms underlying the efflux-mediated resistance in R. equi. METHODS: R. equi ATCC 33701 was stimulated with increasing concentrations of EtBr. The...

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