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Article

Inactivation of DltA modulates virulence factor expression in Streptococcus pyogenes.

PloS one - 1 Jan 2009

Cox Kathleen H, Ruiz-Bustos Eduardo, Courtney Harry S, Dale James B, Pence Morgan A, Nizet Victor, Aziz Ramy K, Gerling Ivan, Price Susan M, Hasty David L

Abstract excerpt

BACKGROUND: D-alanylated lipoteichoic acid is a virtually ubiquitous component of gram-positive cell walls. Mutations in the dltABCD operon of numerous species exhibit pleiotropic effects, including reduced virulence, which has been attributed to increased binding of cationic antimicrobial peptid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19401780
DOI: 10.1371/journal.pone.0005366
PMCID: PMC2671602

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19401780-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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