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Article

The PreS2 activator MHBs(t) of hepatitis B virus activates c-raf-1/Erk2 signaling in transgenic mice.

The EMBO journal - 15 Feb 2002

Hildt Eberhard, Munz Barbara, Saher Gesine, Reifenberg Kurt, Hofschneider Peter Hans

Abstract excerpt

The large hepatitis B virus (HBV) surface protein (LHBs) and C-terminally truncated middle size surface proteins (MHBs(t)) form the family of the PreS2 activator proteins of HBV. Their transcriptional activator function is based on the cytoplasmic orientation of the PreS2 domain. MHBs(t) activators are paradigmatic for this class of activators. Here we report that MHBs(t) is protein kinase C (PKC)-dependently...

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Share to Fluorescent Antibody Technique, Indirect
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitogen-Activated Protein Kinase 1

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Share to Proto-Oncogene Proteins c-raf

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Identifiers

PMID: 11847101
DOI: 10.1093/emboj/21.4.525
PMCID: PMC125852

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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