Article
AmfS, an extracellular peptidic morphogen in Streptomyces griseus.
Journal of bacteriology - 1 Mar 2002
Ueda Kenji, Oinuma Ken-Ichi, Ikeda Go, Hosono Kuniaki, Ohnishi Yasuo, Horinouchi Sueharu, Beppu Teruhiko
Abstract excerpt
The amf gene cluster was previously identified as a regulator for the onset of aerial-mycelium formation in Streptomyces griseus. The nucleotide sequences of amf and its counterparts in other species revealed a conserved gene organization consisting of five open reading frames. A nonsense mutation in amfS, encoding a 43-amino-acid peptide, caused significant blocking of aerial-mycelium formation and streptomycin...
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