Article
Identification of sas, a conserved gene cluster involved in the regulation of aerial mycelium formation in Streptomyces griseus.
Microbiology (Reading, England) - 1 Dec 2008
Takano Hideaki, Tanaka Takumi, Beppu Teruhiko, Ueda Kenji
Abstract excerpt
We cloned a DNA fragment that suppressed the aerial-mycelium-deficient phenotype in an amfS mutant of Streptomyces griseus when it was introduced into the cells via a high-copy-number plasmid. The sasABCDR gene cluster was identified as being responsible for this suppressive activity. The proteins encoded by sasABCD were of unknown function, but the operon structure was found to be conserved in all the strains of...
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