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Dendritic cells pulsed with a tumor-specific peptide induce long-lasting immunity and are effective against murine intracerebral melanoma.

Neurosurgery - 1 Jan 2002

Heimberger Amy B, Archer Gary E, Crotty Laura E, McLendon Roger E, Friedman Allan H, Friedman Henry S, Bigner Darell D, Sampson John H

Abstract excerpt

OBJECTIVE: Dendritic cells (DCs) are specialized cells of the immune system that are capable of generating potent immune responses that are active even within the "immunologically privileged" central nervous system. However, immune responses generated by DCs have also been demonstrated to produce clinically significant autoimmunity. Targeting the epidermal growth factor receptor variant III (EGFRvIII), which is a...

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PMID: 11844246
DOI: 10.1097/00006123-200201000-00024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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