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Article

Epidermal growth factor receptor (EGFR)-retargeted measles virus strains effectively target EGFR- or EGFRvIII expressing gliomas.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 Apr 2007

Paraskevakou Georgia, Allen Cory, Nakamura Takafumi, Zollman Paula, James C David, Peng Kah Whye, Schroeder Mark, Russell Stephen J, Galanis Evanthia

Abstract excerpt

A retargeted measles virus strain MV-GFP-H(AA)-scEGFR was generated by engineering the MV-NSe Edmonston vaccine strain to incorporate both CD46 (Y481A) and signaling lymphocyte activation molecule (SLAM) (R533A) ablating mutations in the hemagglutinin protein in combination with the display of a...

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Source

Identifiers

PMID: 17299404
DOI: 10.1038/sj.mt.6300105

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17299404-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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