Article
Immunization using autologous dendritic cells pulsed with the melanoma-associated antigen gp100-derived G280-9V peptide elicits CD8+ immunity.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2005
Linette Gerald P, Zhang Dongsheng, Hodi F Stephen, Jonasch Eric P, Longerich Simonne, Stowell Christopher P, Webb Iain J, Daley Heather, Soiffer Robert J, Cheung Amy M, Eapen Sara G, Fee Sharon V, Rubin Krista M, Sober Arthur J, Haluska Frank G
Abstract excerpt
PURPOSE: To determine the toxicity, maximal tolerated dose, and clinical and immunologic response to autologous dendritic cells pulsed with melanoma-associated antigen gp100-derived G280-9V peptide. PATIENTS AND METHODS: Twelve HLA-A*0201(+) patients with advanced melanoma were administered dendritic cells pulsed with G280-9V peptide. Cohorts of three patients were administered 5 x 10(6), 15 x 10(6), and 50 x...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
