Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BAX and p16INK4Aare independent positive prognostic markers for advanced tumour stage of nonsmall cell lung cancer

1 Jan 2002

Abstract excerpt

Clinical studies suggest prognostic relevance of p16INK4A in nonsmall cell lung cancer (NSCLC) while conflicting results for p53 have been published. However, the importance of the apoptosis regulating gene BAX, a downstream regulator of p53, on the prognosis of NSCLC is unknown. The present study investigated the prognostic relevance of BAX with respect to the status of p53 and P16INK4A in 61 patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer-related Molecular Pathways
Share to Lung Cancer Treatments and Mutations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11843312
DOI: 10.1183/09031936.02.00219402

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BAX and p16INK4Aare independent positive prognostic markers for advanced tumour stage of nonsmall cell lung cancerPMID 11843312Read ↗

Overexpression of bax associated with mutations in the loop-sheet-helix motif of p53.Semantic proximity Read ↗

Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis.Semantic proximity Read ↗

Studies on p53, BAX and Bcl-2 protein expression and microsatellite instability in stage III (UICC) colon cancer treated by adjuvant chemotherapy: major prognostic impact of proapoptotic BAXSemantic proximity Read ↗

Analysis of p53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors.Semantic proximity Read ↗

Reduced ING1b gene expression plays an important role in carcinogenesis of non-small cell lung cancer patients.Semantic proximity Read ↗

The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patientsSemantic proximity Read ↗

p53 mutant immunophenotype and deregulation of p53 transcription pathway (Bcl2, Bax, and Waf1) in precursor bronchial lesions of lung cancer.Semantic proximity Read ↗

Immunohistochemical and molecular analysis of bax, bcl-2 and p53 genes in laryngeal squamous cell carcinomas.Semantic proximity Read ↗

Prognostic implications of BAX protein expression and microsatellite instability in all non-metastatic stages of primary colon cancer treated by surgery alone.Semantic proximity Read ↗

Inhibition of the NF-kappa B transcription factor increases Bax expression in cancer cell lines.Semantic proximity Read ↗

Expression of apoptosis regulatory proteins of the Bcl-2 family and p53 in primary resected non-small-cell lung cancerSemantic proximity Read ↗

Evaluation of Bax and Bak gene mutations and expression in breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.