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Article

The novel BLM3 gene encodes a protein that protects against lethal effects of oxidative damage.

Cellular and molecular biology (Noisy-le-Grand, France) - 1 Nov 2001

Febres D E, Pramanik A, Caton M, Doherty K, McKoy J, Garcia E, Alejo W, Moore C W

Abstract excerpt

Mutational alteration of the BLM3 gene in Saccharomyces cerevisiae confers hypersensitivities to lethal effects of ionizing radiation, anticancer bleomycins and structurally-related phleomycins. Bleomycin is used clinically in the treatment of many types of cancers, including Kaposi's sarcoma. The BLM3 gene was cloned from a genomic library by complementing the drug hypersensitivities conferred by the codominant...

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PMID: 11842813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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