Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of translation initiation factor eIF4B with the poliovirus internal ribosome entry site.

Journal of virology - 1 Mar 2002

Ochs Kerstin, Saleh Lanja, Bassili Gergis, Sonntag Volker H, Zeller Amandus, Niepmann Michael

Abstract excerpt

Poliovirus translation is initiated at the internal ribosome entry site (IRES). Most likely involving the action of standard initiation factors, this highly structured cis element in the 5" noncoding region of the viral RNA guides the ribosome to an internal silent AUG. The actual start codon for viral protein synthesis further downstream is then reached by ribosomal scanning. In this study we show that two of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions
Share to Eukaryotic Initiation Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Peptide Initiation Factors

Share to Poliovirus

Share to Polypyrimidine Tract-Binding Protein

Share to Ribonucleoproteins

Share to Ribosomal Proteins

Share to Ribosomes

Source

Open in PubMed Open full text

Identifiers

PMID: 11836388
DOI: 10.1128/jvi.76.5.2113-2122.2002
PMCID: PMC135939

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of translation initiation factor eIF4B with the poliovirus internal ribosome entry site.PMID 11836388Read ↗

Physical association of eukaryotic initiation factor 4G (eIF4G) with eIF4A strongly enhances binding of eIF4G to the internal ribosomal entry site of encephalomyocarditis virus and is required for internal initiation of translation.Semantic proximity Read ↗

RNA-Binding Proteins as Regulators of Internal Initiation of Viral mRNA TranslationSemantic proximity Read ↗

Interaction of the eIF4G initiation factor with the aphthovirus IRES is essential for internal translation initiation in vivo.Semantic proximity Read ↗

IRES interaction with translation initiation factors: Functional characterization of novel RNA contacts with eIF3, eIF4B, and eIF4GIISemantic proximity Read ↗

Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodelingSemantic proximity Read ↗

Functional involvement of polypyrimidine tract-binding protein in translation initiation complexes with the internal ribosome entry site of foot-and-mouth disease virusSemantic proximity Read ↗

Polypyrimidine Tract-Binding Protein Regulates Enterovirus 71 Translation Through Interaction with the Internal Ribosomal Entry SiteSemantic proximity Read ↗

Viral Internal Ribosome Entry Site Elements: Novel Ribosome-RNA Complexes and Roles in Viral PathogenesisSemantic proximity Read ↗

The Translation Initiation Factor eIF-4E Binds to a Common Motif Shared by the Translation Factor eIF-4γ and the Translational Repressors 4E-Binding ProteinsSemantic proximity Read ↗

Coordinated movements of eukaryotic translation initiation factors eIF1, eIF1A, and eIF5 trigger phosphate release from eIF2 in response to start codon recognition by the ribosomal preinitiation complex.Semantic proximity Read ↗

Evidence for an RNA chaperone function of polypyrimidine tract-binding protein in picornavirus translationSemantic proximity Read ↗

Minimum internal ribosome entry site required for poliovirus infectivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.