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Article

Loss of p53 accelerates neointimal lesions of vein bypass grafts in mice.

Circulation research - 8 Feb 2002

Mayr Ursula, Mayr Manuel, Li Chaohong, Wernig Florian, Dietrich Hermann, Hu Yanhua, Xu Qingbo

Abstract excerpt

The transcription factor p53 is essentially involved in regulation of cell death and proliferation. Recently, we have established a mouse model for vein graft arteriosclerosis by grafting autologous jugular veins or vena cava to carotid arteries. Using this model, we studied the role of p53 in the development of vein graft arteriosclerosis in p53(-/-) mice. Four weeks after grafting, neointimal hyperplasia of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11834713
DOI: 10.1161/hh0202.103715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Loss of p53 accelerates neointimal lesions of vein bypass grafts in mice.PMID 11834713Read ↗

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