Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of p53 accelerates neointimal lesions of vein bypass grafts in mice.

Circulation research - 8 Feb 2002

Mayr Ursula, Mayr Manuel, Li Chaohong, Wernig Florian, Dietrich Hermann, Hu Yanhua, Xu Qingbo

Abstract excerpt

The transcription factor p53 is essentially involved in regulation of cell death and proliferation. Recently, we have established a mouse model for vein graft arteriosclerosis by grafting autologous jugular veins or vena cava to carotid arteries. Using this model, we studied the role of p53 in th...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carotid Arteries
Share to In Situ Nick-End Labeling
Share to Macrophage-1 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Mutant Strains

Share to Muscle, Smooth, Vascular

Share to Nitroprusside

Share to Transplantation, Autologous

Source

Identifiers

PMID: 11834713
DOI: 10.1161/hh0202.103715

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11834713-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of p53 accelerates neointimal lesions of vein bypass grafts in mice.PMID 11834713Read ↗

Rapid development of vein graft atheroma in ApoE-deficient mice.Semantic proximity Read ↗

Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.Semantic proximity Read ↗

Accelerated arteriosclerosis of vein grafts in inducible NO synthase(-/-) mice is related to decreased endothelial progenitor cell repair.Semantic proximity Read ↗

γ-Secretase inhibitor DAPT attenuates intimal hyperplasia of vein grafts by inhibition of Notch1 signaling.Semantic proximity Read ↗

Macrophage-specific p53 expression plays a crucial role in atherosclerosis development and plaque remodeling.Semantic proximity Read ↗

Calcium channel antagonist verapamil inhibits neointimal formation and enhances apoptosis in a vascular graft model.Semantic proximity Read ↗

Reduced apoptosis and increased lesion development in the flow-restricted carotid artery of p75(NTR)-null mutant mice.Semantic proximity Read ↗

Induction of p53 by GKLF is essential for inhibition of proliferation of vascular smooth muscle cellsSemantic proximity Read ↗

Inhibitor of apoptosis protein survivin regulates vascular injury.Semantic proximity Read ↗

Plgf-/-eNos-/- mice show defective angiogenesis associated with increased oxidative stress in response to tissue ischemia.Semantic proximity Read ↗

Caveolin-1 deficiency stimulates neointima formation during vascular injury.Semantic proximity Read ↗

Loss of p53 compensates for alpha v-integrin function in retinal neovascularization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.