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Article

Immunity to intracellular pathogens as a complex genetic trait.

Current opinion in microbiology - 1 Feb 2002

Kramnik Igor, Boyartchuk Victor

Abstract excerpt

Although the role of host heredity in susceptibility to infectious diseases is significant, the genetic control of immunity to infection remains poorly understood. Advances in experimental and epidemiological analyses of complex genetic traits have led to the discoveries of novel genetic determinants of host resistance. New loci that control susceptibility to a number of intracellular pathogens have been...

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PMID: 11834379
DOI: 10.1016/s1369-5274(02)00295-3

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