Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevention of auditory dysfunction in hypothyroid Tshr mutant mice by thyroxin treatment during development.

Journal of the Association for Research in Otolaryngology : JARO - 1 Dec 2001

Sprenkle P M, McGee J, Bertoni J M, Walsh E J

Abstract excerpt

Based on previous work, it is clear that genetically hypothyroid Tshr(hyt) mutant mice are congenitally deaf [O'Malley et al. (1995) Hear. Res. 88: 181-189, Sprinkle et al. 2001b, J. Assoc. Res. Otolaryngol. DOI: 10.1007/s101620010077]. However, the extent to which auditory development is dependent on the availability of thyroxin (T4) during specific developmental stages is unknown. The aim of this study was to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Auditory Threshold
Share to Evoked Potentials, Auditory, Brain Stem

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hearing Disorders

Share to Hypothyroidism

Share to Reaction Time

Share to Receptors, Thyrotropin

Share to Thyroxine

Source

Open in PubMed Open full text

Identifiers

PMID: 11833608
DOI: 10.1007/s101620010078
PMCID: PMC3201071

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevention of auditory dysfunction in hypothyroid Tshr mutant mice by thyroxin treatment during development.PMID 11833608Read ↗

Development of auditory brainstem responses (ABRs) in Tshr mutant mice derived from euthyroid and hypothyroid dams.Semantic proximity Read ↗

Consequences of hypothyroidism on auditory system function in Tshr mutant (hyt) mice.Semantic proximity Read ↗

Requirement of thyrotropin-releasing hormone for the postnatal functions of pituitary thyrotrophs: ontogeny study of congenital tertiary hypothyroidism in mice.Semantic proximity Read ↗

The influence of thyroid hormone deficiency on the development of cochlear nonlinearities.Semantic proximity Read ↗

Knock-in mouse model for resistance to thyroid hormone (RTH): an RTH mutation in the thyroid hormone receptor beta gene disrupts cochlear morphogenesis.Semantic proximity Read ↗

Thyroid hormone receptor beta is essential for development of auditory function.Semantic proximity Read ↗

Mice lacking the thyrotropin-releasing hormone gene: what do they tell us?Semantic proximity Read ↗

Genetic analysis of thyroid hormone receptors in development and disease.Semantic proximity Read ↗

Altered Craniofacial and Bone Morphology in Hyperthyroid Knock-In Mice Carrying TSHR D633H and M453T Mutations.Semantic proximity Read ↗

Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation.Semantic proximity Read ↗

The Dual Roles of Triiodothyronine in Regulating the Morphology of Hair Cells and Supporting Cells during Critical Periods of Mouse Cochlear DevelopmentSemantic proximity Read ↗

Retardation of cochlear maturation and impaired hair cell function caused by deletion of all known thyroid hormone receptors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.