Article
Consequences of hypothyroidism on auditory system function in Tshr mutant (hyt) mice.
Journal of the Association for Research in Otolaryngology : JARO - 1 Dec 2001
Sprenkle P M, McGee J, Bertoni J M, Walsh E J
Abstract excerpt
The otological consequences of hypothyroidism and the outcome of thyroxin (T4) administration during the developmental period preceding the onset of hearing were examined in mice that express a point mutation in the gene encoding the thyrotropin receptor (Tshr), the so-called hyt mouse. Progeny of sires homozygous for the trait and heterozygous dams were injected with T4 or saline placebo from birth through the...
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