Article
Association between chromosome 1p and 19q loss and outcome in pediatric malignant gliomas: results from the CCG-945 cohort.
Pediatric neurosurgery - 1 Sept 2003
Pollack Ian F, Finkelstein Sydney D, Burnham Judith, Hamilton Ronald L, Yates Allan J, Holmes Emiko J, Boyett James M, Finlay Jonathan L
Abstract excerpt
BACKGROUND: Results of recent molecular studies on malignant gliomas in adults showed that deletions within the short arm of chromosome 1 and/or the long arm of chromosome 19 identified a prognostically favorable subgroup of tumors that often respond to conventional chemotherapy. To determine if...
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