Article
Phenotype and envelope gene diversity of nef-deleted HIV-1 isolated from long-term survivors infected from a single source.
Virology journal - 16 Jul 2007
Gray Lachlan, Churchill Melissa J, Sterjovski Jasminka, Witlox Kristie, Learmont Jennifer C, Sullivan John S, Wesselingh Steven L, Gabuzda Dana, Cunningham Anthony L, McPhee Dale A, Gorry Paul R
Abstract excerpt
BACKGROUND: The Sydney blood bank cohort (SBBC) of long-term survivors consists of multiple individuals infected with attenuated, nef-deleted variants of human immunodeficiency virus type 1 (HIV-1) acquired from a single source. Long-term prospective studies have demonstrated that the SBBC now comprises slow progressors (SP) as well as long-term nonprogressors (LTNP). Convergent evolution of nef sequences in SBBC...
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