Article
Mechanical tension in distraction osteogenesis regulates chondrocytic differentiation.
International journal of oral and maxillofacial surgery - 1 Dec 2001
Meyer U, Meyer T, Wiesmann H P, Kruse-Lösler B, Vollmer D, Stratmann U, Joos U
Abstract excerpt
Differentiation of chondrocytes to cells of osteoblastic phenotype occurs during an interim period of bone development, fracture repair and distraction osteogenesis. To study the relationship between tension-stress and chondrogenesis, uniaxial strains (0 microstrains, 2000 microstrains, 20000 microstrains, 200000 microstrains, 300000 microstrains) were applied in a rabbit model of mandibular distraction...
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