Article
Genomic structure of the human beta-PIX gene and its alteration in gastric cancer.
Cancer letters - 28 Mar 2002
Li Zhong you, Wang You jie, Song Jian ping, Kataoka Hideki, Yoshii Shigeto, Gao Chang ming, Wang Ya ping, Zhou Jian nong, Ota Satoshi, Tanaka Masamitsu, Sugimura Haruhiko
Abstract excerpt
beta-PIX, a newly identified p21-activated kinase (PAK)-interacting exchange factors (PIX), encodes a guanine nucleotide exchange factor for Rho guanosine triphosphatases. Characterization of beta-PIX gene was performed using the BAC Library method. The beta-PIX gene has 17 exons and an A/T polymorphism at the 32nd base upstream of the intron/exon junction of exon 7. The frequencies of genotypes A/T, A/A and T/T...
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