Genomic landscape of gastric cancer: molecular classification and potential targets.

doi:10.1007/s11427-016-0034-1

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Article

Genomic landscape of gastric cancer: molecular classification and potential targets.

Science China. Life sciences - 1 Feb 2017

Guo Jiawei, Yu Weiwei, Su Hui, Pang Xiufeng

Abstract excerpt

Gastric cancer imposes a considerable health burden worldwide, and its mortality ranks as the second highest for all types of cancers. The limited knowledge of the molecular mechanisms underlying gastric cancer tumorigenesis hinders the development of therapeutic strategies. However, ongoing collaborative sequencing efforts facilitate molecular classification and unveil the genomic landscape of gastric cancer....

Topics

Chromatin Assembly and Disassembly
DNA Methylation
Gene Expression Regulation, Neoplastic
Genomics
Humans
Mutation
Receptor Protein-Tyrosine Kinases
Stem Cells
Stomach Neoplasms
Tumor Suppressor Protein p53
rhoA GTP-Binding Protein

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Identifiers

PMID: 27460193
DOI: 10.1007/s11427-016-0034-1

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