Article
Genomic structure of human alpha-pix, and variable deletions in a poly (T) tract in gastric cancer tissue.
Cancer letters - 10 Mar 2001
Wang Y J, Oba S M, Yoshii S, Song J P, Wang Y, Kanamori M, Ota S, Tanaka M, Sugimura H
Abstract excerpt
PAK-interacting exchange factor (PIX) has been reported to mediate the recruitment of PAK into focal adhesions and activate Rac, thus creating a feedback loop that stimulate PAK and other targets. This pathway is thought to be related to cellular changes, such as transformation and migration, that are often encountered in cancer cells. Here, we report the genomic structure of alpha-PIX, one of the PAK-...
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