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Article

Coagulation factor XII activity, but not an associated common genetic polymorphism (46C/T),is linked to recurrent miscarriage.

Fertility and sterility - 1 Feb 2002

Iinuma Yoshiro, Sugiura-Ogasawara Mayumi, Makino Aiko, Ozaki Yasuhiko, Suzumori Nobuhiro, Suzumori Kaoru

Abstract excerpt

OBJECTIVE: To investigate whether a factor XII genetic polymorphism is associated with first-trimester embryonal loss. DESIGN: Prospective case-control study. SETTING; Nagoya City University Hospital. PATIENT(S): Eighty-three patients with a history of two or more unexplained first-trimester recurrent miscarriages and 67 controls with no obstetric complications or history of miscarriage. MAIN OUTCOME MEASURE(S):...

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Identifiers

PMID: 11821096
DOI: 10.1016/s0015-0282(01)02989-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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