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Article

Which thrombophilic gene mutations are risk factors for recurrent pregnancy loss?

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Oct 2006

Goodman Cyle S, Coulam Carolyn B, Jeyendran Rajasingam S, Acosta Vida A, Roussev Roumen

Abstract excerpt

PROBLEM: Thrombophilia has been associated with poor obstetrical outcomes. To determine the association of specific inherited thrombophilias and recurrent pregnancy loss, 10 thrombophilic genes were investigated. METHOD OF STUDY: A total of 550 women with a history of recurrent pregnancy loss had buccal swabs taken for DNA analyses of the following gene mutations: factor V G1691A, factor V H1299R (R2), factor V...

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Source

Identifiers

PMID: 16938111
DOI: 10.1111/j.1600-0897.2006.00419.x

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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