Article
Comparison of thrombophilic gene mutations among patients experiencing recurrent miscarriage and deep vein thrombosis.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Nov 2008
Coulam Carolyn B, Wallis Diane, Weinstein Jordan, DasGupta Dipankar S, Jeyendran Rajasingam S
Abstract excerpt
PROBLEM: Inherited thrombophilia has been shown to be a risk factor for cardiovascular disease including deep venous thrombosis as well as reproductive disorders including recurrent pregnancy loss. We have previously reported three out of the 10 thrombophilic mutations studied, plasminogen activator inhibitor-1 (PAI-1) 4G/5G, factor XIII V34L, and homozygous MTHFR C667T, correlated significantly with recurrent...
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