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Article

Genotyping analysis for the 46 C/T polymorphism of coagulation factor XII and the involvement of factor XII activity in patients with recurrent pregnancy loss.

PloS one - 1 Jan 2014

Asano Eriko, Ebara Takeshi, Yamada-Namikawa Chisato, Kitaori Tamao, Suzumori Nobuhiro, Katano Kinue, Ozaki Yasuhiko, Nakanishi Makoto, Sugiura-Ogasawara Mayumi

Abstract excerpt

BACKGROUND: Established causes of recurrent pregnancy loss (RPL) include antiphospholipid syndrome, uterine anomalies, parental chromosomal abnormalities, particularly translocations and abnormal embryonic karyotype. A systematic review concluded that coagulation factor XII (FXII) deficiency was associated with RPL. However, it could not be established whether the 46 C/T SNP of FXII or low activity of FXII was a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25489738
DOI: 10.1371/journal.pone.0114452
PMCID: PMC4260909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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