Article
Revisiting the Link Between Factor XII and Recurrent Pregnancy Loss: A Scoping Review
1 Aug 2025
Abstract excerpt
Pregnancy loss affects approximately 23% of women, with 1%-3% experiencing recurrent pregnancy loss (RPL), defined as two or more consecutive miscarriages. Despite extensive research, up to 50% of RPL cases remain unexplained, making it a complex issue in reproductive medicine. Coagulation Factor XII (FXII) a key component of the contact activation pathway, has been suggested to play a role in RPL. Low FXII...
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