Article
+1040 C/T polymorphism in coding region of thrombin-activatable fibrinolysis inhibitor gene and the risk of idiopathic recurrent fetal loss.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Oct 2010
Pruner Iva, Djordjevic Valentina, Miljic Predrag, Kovac Mirjana, Antonijevic Nebojsa, Rakicevic Ljiljana, Radojkovic Dragica
Abstract excerpt
Recurrent fetal loss (RFL) is common health problem affecting up to 5% of women of reproductive age. It has been shown that plasma thrombin-activatable fibrinolysis inhibitor (TAFI) concentrations increase during pregnancy and return to baseline levels soon after delivery. The +1040C/T single nucleotide polymorphism in coding region of TAFI gene is associated with TAFI blood levels. The aim of our study was to...
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