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Article

p8 is critical for tumour development induced by rasV12 mutated protein and E1A oncogene.

EMBO reports - 1 Feb 2002

Vasseur Sophie, Hoffmeister Albrecht, Garcia Stephane, Bagnis Claude, Dagorn Jean-Charles, Iovanna Juan Lucio

Abstract excerpt

The p8 protein is involved in the cellular stress response of many tissues. Because p8 is overexpressed in many cancers, we investigated whether its expression was required for tumour development. Mouse embryo fibroblasts (MEFs) from p8+/+ and p8-/- animals were transformed with the pBabe-rasV12/E1A retroviral vector, which expresses both the rasV12 mutated protein and the E1A oncogene. As expected, transformed...

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Share to Adenovirus E1A Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11818333
DOI: 10.1093/embo-reports/kvf023
PMCID: PMC1083964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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