Article
Double mutant and formaldehyde inactivated TSST-1 as vaccine candidates for TSST-1-induced toxic shock syndrome.
Vaccine - 31 Jan 2002
Gampfer Jörg, Thon Vojtech, Gulle Heinz, Wolf Hermann M, Eibl Martha M
Abstract excerpt
Up to now there is no treatment for staphylococcal toxic shock syndrome, a disease mainly induced by toxic shock syndrome toxin-1(TSST-1). There is great demand in finding means to control the disease, one of them is the development of an effective and safe vaccine against TSST-1. In this study we constructed a series of vaccine candidates and investigated their biological activity, toxicity, and potential to...
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