Article
Protein S levels and the risk of venous thrombosis: results from the MEGA case-control study.
Blood - 31 Oct 2013
Pintao Maria Carolina, Ribeiro Daniel D, Bezemer Irene D, Garcia Andrea A, de Visser Marieke C H, Doggen Carine J M, Lijfering Willem M, Reitsma Pieter H, Rosendaal Frits R
Abstract excerpt
In thrombophilic families, protein S deficiency is clearly associated with venous thrombosis. We aimed to determine whether the same holds true in a population-based case-control study (n = 5317). Subjects were regarded protein S deficient when protein S levels were < 2.5th percentile of the controls. Free and total protein S deficiency was not associated with venous thrombosis: free protein S < 53 U/dL, odds...
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