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Article

Germ cells microsatellite instability. The effect of different mutagens in a mismatch repair mutant of Drosophila (spel1).

Mutation research - 15 Feb 2002

López A, Xamena N, Marcos R, Velázquez A

Abstract excerpt

Mismatch repair (MMR) process confers a type of genomic stability that maintains stable single repeated sequences, hence a failure of this process could deviate in cancer development. A characteristic phenotype of MMR-deficient cells is microsatellite instability (MSI) that could be modulated by mutagenic agents. The induction of MSI by the mutagens, bleomycin (BLM), hydrogen peroxide (H(2)O(2)),...

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Identifiers

PMID: 11815247
DOI: 10.1016/s1383-5718(01)00325-4

Genes

BLM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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