Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Are selective endothelin A receptor antagonists better than mixed antagonists?

Journal of cardiovascular pharmacology - 1 Nov 2001

Bagnall A, Webb D

Abstract excerpt

Pharmacological antagonism of the endothelin system presents a novel target for the treatment of a range of cardiovascular diseases. The antagonists developed so far differ in their endothelin receptor subtype specificity. Indeed, at present there is no consensus opinion as to what level of receptor selectivity defines a particular antagonist as 'selective' or 'mixed'. Antagonists that are highly selective for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amiloride
Share to Angiotensin-Converting Enzyme Inhibitors
Share to Antihypertensive Agents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Endothelium, Vascular

Share to Receptor, Endothelin A

Share to Receptor, Endothelin B

Share to Receptors, Endothelin

Share to Vasodilation

Source

Identifiers

PMID: 11811376
DOI: 10.1097/00005344-200111002-00011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Are selective endothelin A receptor antagonists better than mixed antagonists?PMID 11811376Read ↗

Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay.Semantic proximity Read ↗

Distinct ETA receptor binding mode of macitentan as determined by site directed mutagenesis.Semantic proximity Read ↗

Pharmacologically distinct phenotypes of α1B -adrenoceptors: variation in binding and functional affinities for antagonists.Semantic proximity Read ↗

Identification of critical extracellular loop residues involved in alpha 1-adrenergic receptor subtype-selective antagonist binding.Semantic proximity Read ↗

Role of the alpha1D-adrenergic receptor in the development of salt-induced hypertension.Semantic proximity Read ↗

Dual agonistic and antagonistic property of nonpeptide angiotensin AT1 ligands: susceptibility to receptor mutations.Semantic proximity Read ↗

Binding characteristics of [3H]-JSM10292: a new cell membrane-permeant non-peptide bradykinin B2 receptor antagonist.Semantic proximity Read ↗

Dual endothelin receptor antagonists contrast the effects induced by endothelin-1 on cultured human microvascular endothelial cells.Semantic proximity Read ↗

Subtype-selective GABAA receptor mimetics—novel antihyperalgesic agents?Semantic proximity Read ↗

Functional ET(A)-ET(B) Receptor Cross-talk in Basilar Artery In Situ From ET(B) Receptor Deficient Rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.