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Article

Pharmacologically distinct phenotypes of α1B -adrenoceptors: variation in binding and functional affinities for antagonists.

British journal of pharmacology - 1 Nov 2014

Yoshiki Hatsumi, Uwada Junsuke, Anisuzzaman Abu Syed Md, Umada Hidenori, Hayashi Ryoji, Kainoh Mie, Masuoka Takayoshi, Nishio Matomo, Muramatsu Ikunobu

Abstract excerpt

BACKGROUND AND PURPOSE: The pharmacological properties of particular receptors have recently been suggested to vary under different conditions. We compared the pharmacological properties of the α1B -adrenoceptor subtype in various tissue preparations and under various conditions. EXPERIMENTAL APPROACH: [(3) H]-prazosin binding to α1B -adrenoceptors in rat liver (segments, dispersed hepatocytes and homogenates)...

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Identifiers

PMID: 24923551
DOI: 10.1111/bph.12813
PMCID: PMC4294112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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