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Article

Trans-complementation of a genetic defect in the coxsackie B3 virus 2B protein.

The Journal of general virology - 1 Feb 2002

van Kuppeveld Frank J M, van den Hurk Patrick J J C, Schrama Ina W J, Galama Jochem M D, Melchers Willem J G

Abstract excerpt

The enterovirus 2B protein contains a putative amphipathic alpha-helix that includes three positively charged and one negatively charged residue. Previously, we observed that replacement of the glutamic acid-40 residue with a lysine residue (mutation 2B-E[40]K) in the amphipathic alpha-helix of the coxsackie B3 virus 2B protein resulted in a quasi-infectious phenotype. On one occasion, however, transfection of...

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Identifiers

PMID: 11807227
DOI: 10.1099/0022-1317-83-2-341

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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