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Article

Restoration of function of carboxy-terminally truncated pseudorabies virus glycoprotein B by point mutations in the ectodomain.

Journal of virology - 1 Dec 2001

Nixdorf R, Klupp B G, Mettenleiter T C

Abstract excerpt

Glycoprotein B (gB) of pseudorabies virus (PrV) is essential for virus entry into target cells and direct viral cell-to-cell spread. Recently, we described a carboxy-terminally truncated derivative of PrV gB, gB-007, which was inefficiently incorporated into virions, was unable to complement infectivity, but was fully capable of restoring direct viral cell-to-cell spread of gB-negative PrV (R. Nixdorf, B. G....

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Identifiers

PMID: 11689634
DOI: 10.1128/JVI.75.23.11526-11533.2001
PMCID: PMC114739

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