Article
Evidence for positive selection and population structure at the human MAO-A gene.
Proceedings of the National Academy of Sciences of the United States of America - 22 Jan 2002
Gilad Yoav, Rosenberg Shai, Przeworski Molly, Lancet Doron, Skorecki Karl
Abstract excerpt
We report the analysis of human nucleotide diversity at a genetic locus known to be involved in a behavioral phenotype, the monoamine oxidase A gene. Sequencing of five regions totaling 18.8 kb and spanning 90 kb of the monoamine oxidase A gene was carried out in 56 male individuals from seven different ethnogeographic groups. We uncovered 41 segregating sites, which formed 46 distinct haplotypes. A permutation...
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