Article
Creating hetero-11-mers composed of wild-type and mutant subunits to study RNA binding to TRAP.
The Journal of biological chemistry - 5 Apr 2002
Li Pan T X, Scott David J, Gollnick Paul
Abstract excerpt
TRAP (trp RNA-binding attenuation protein) is an RNA-binding protein that regulates expression of the tryptophan biosynthetic genes in Bacillus subtilis by binding to RNA targets that contain multiple GAG and UAG repeats. TRAP is composed of 11 identical subunits arranged symmetrically in a ring. The secondary structure of the protein consists entirely of antiparallel beta-sheets, beta-turns, and loops. We show...
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