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Article

Fish oil feeding alters liver gene expressions to defend against PPARalpha activation and ROS production.

American journal of physiology. Gastrointestinal and liver physiology - 1 Feb 2002

Takahashi Mayumi, Tsuboyama-Kasaoka Nobuyo, Nakatani Teruyo, Ishii Masami, Tsutsumi Shuichi, Aburatani Hiroyuki, Ezaki Osamu

Abstract excerpt

Fish oil rich in n-3 polyunsaturated fatty acids has been shown to reduce the risk of cardiovascular diseases partly by reduction of blood triglyceride concentration. This favorable effect mainly results from the combined effects of inhibition of lipogenesis by decrease of SREBP-1 and stimulation of fatty acid oxidation by activation of peroxisome proliferator-activated receptor-alpha (PPARalpha) in liver....

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Identifiers

PMID: 11804856
DOI: 10.1152/ajpgi.00376.2001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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