Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene expression profiling of potential PPARγ target genes in mouse aorta

6 Apr 2004

Abstract excerpt

Diminished activity of peroxisome proliferator-activated receptor-gamma (PPARgamma) may play a role in the pathogenesis of hypertension and vascular dysfunction. To better understand what genes are regulated by PPARgamma, an experimental data set was generated by microarray analysis, in duplicate, of pooled aortic mRNA isolated from mice treated for 21 days with a PPARgamma agonist (rosiglitazone) or vehicle. Of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Inflammatory mediators and NSAID effects
Share to Peroxisome Proliferator-Activated Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15054141
DOI: 10.1152/physiolgenomics.00027.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene expression profiling of potential PPARγ target genes in mouse aortaPMID 15054141Read ↗

Bioinformatic analysis of gene sets regulated by ligand-activated and dominant-negative peroxisome proliferator-activated receptor gamma in mouse aorta.Semantic proximity Read ↗

Interference with PPAR gamma function in smooth muscle causes vascular dysfunction and hypertension.Semantic proximity Read ↗

Transcriptomic analysis of aorta from a short-term high-fat diet fed mouse reveals changes in the expression of vessel structure genes.Semantic proximity Read ↗

Microarray analysis of gene expression in mouse aorta reveals role of the calcium signaling pathway in control of atherosclerosis susceptibility.Semantic proximity Read ↗

Does peroxisome proliferator-activated receptor-gamma (PPAR gamma) protect from hypertension directly through effects in the vasculature?Semantic proximity Read ↗

Effect of PPARγ inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertensionSemantic proximity Read ↗

A systematic analysis of 40 random genes in cultured vascular smooth muscle subtypes reveals a heterogeneity of gene expression and identifies the tight junction gene zonula occludens 2 as a marker of epithelioid "pup" smooth muscle cells and a participant in carotid neointimal formation.Semantic proximity Read ↗

Functional Genomics Validation of PPAR gamma Signalling in PASMCs: Therapeutic Implications for Pulmonary Arterial HypertensionSemantic proximity Read ↗

Characterization of the mouse peroxisome proliferator-activated receptor delta gene.Semantic proximity Read ↗

The effects of PPARβ/δ ligands on lung inflammation and vascular reactivitySemantic proximity Read ↗

Comparative Analysis of Gene Regulation by the Transcription Factor PPARα between Mouse and HumanSemantic proximity Read ↗

PPARs: Regulators of Metabolism and As Therapeutic Targets in Cardiovascular disease. Part I: PPAR-αSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.