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Article

Structural requirements for palmitoylation of surfactant protein C precursor.

The Biochemical journal - 1 Feb 2002

ten Brinke Anja, Vaandrager Arie B, Haagsman Henk P, Ridder Anja N J A, van Golde Lambert M G, Batenburg Joseph J

Abstract excerpt

Pulmonary surfactant protein C (SP-C) propeptide (proSP-C) is a type II transmembrane protein that is palmitoylated on two cysteines adjacent to its transmembrane domain. To study the structural requirements for palmitoylation of proSP-C, His-tagged human proSP-C and mutant forms were expressed in Chinese hamster ovary cells and analysed by metabolic labelling with [3H]palmitate. Mutations were made in the amino...

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Identifiers

PMID: 11802797
DOI: 10.1042/0264-6021:3610663
PMCID: PMC1222350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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