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Article

Processing of surfactant protein C requires a type II transmembrane topology directed by juxtamembrane positively charged residues.

The Journal of biological chemistry - 28 Nov 2003

Mulugeta Surafel, Beers Michael F

Abstract excerpt

Surfactant protein C (SP-C) is a lung-specific protein that is synthesized as a 21-kDa integral membrane propeptide (pro-SP-C) and proteolytically processed to a 3.7-kDa secretory product. Previous studies have shown that palmitoylation of pro-SP-C is dependent on two N-terminal juxtamembrane pos...

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PMID: 12933801
DOI: 10.1074/jbc.M308210200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12933801-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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