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Article

Surfactant protein C biosynthesis and its emerging role in conformational lung disease.

Annual review of physiology - 1 Jan 2005

Beers Michael F, Mulugeta Surafel

Abstract excerpt

Surfactant protein C (SP-C) is a hydrophobic 35-amino acid peptide that co-isolates with the phospholipid fraction of lung surfactant. SP-C represents a structurally and functionally challenging protein for the alveolar type 2 cell, which must synthesize, traffic, and process a 191-197-amino acid precursor protein through the regulated secretory pathway. The current understanding of SP-C biosynthesis considers...

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PMID: 15709974
DOI: 10.1146/annurev.physiol.67.040403.101937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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