Article
Mouse hepatocyte growth factor (HGF) activator inhibitor type 2 lacking the first Kunitz domain potently inhibits the HGF activator.
Biochemical and biophysical research communications - 25 Jan 2002
Kataoka Hiroaki, Itoh Hiroshi, Nuki Yoshitsugu, Hamasuna Ryouichi, Naganuma Seiji, Kitamura Naomi, Shimomura Takeshi
Abstract excerpt
Hepatocyte growth factor activator inhibitor type 2 (HAI-2) is a serine proteinase inhibitor containing two Kunitz-type inhibitor domains, initially identified as a potent inhibitor of hepatocyte growth factor activator (HGFA). In a previous study (Biochem. Biophys. Res. Commun. 255, 740-748, 1999), we reported that a predominant transcript of mouse HAI-2 is a splicing variant lacking the first Kunitz domain...
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